It isn't quite clear what you're trying to. Are you saying you have something like:

and you want:

If you want to change 'in place', then a simple Find and Replace will do the job. Edit -> Find...:

This will replace all occurrences of 'https://' with an empty string.
If you want to retain the original URL and just extract the hostname and/or path from the URL, then you need an adjacent column with some text functions to strip the protocol:

Formula in F2 is:
=TEXTAFTER(E2,"https://",1)
which returns all the text after 'https://' (note this may be more complicated with more complex URLs, but I can't see what you're working with.