The first thing to do is uninstall sophos.
It is not giving you any protection and is hurting performance.
Effective defenses against malware and other threats
The version of Parallels is very old. The current one is 17, you have 11. This almost certainly does not work in Big Sur, and could be causing issues.
[Loaded] com.google.keystone.daemon.plist (Google, Inc. - installed 2021-08-23)
[Loaded] com.google.keystone.agent.plist (Google, Inc. - installed 2021-08-23)
[Loaded] com.google.keystone.xpcservice.plist (Google, Inc. - installed 2021-08-23)
Google and its keystone daemons are well known enemies of professional, and especially video applications.
You should uninstall completely, and then drag Motion to the trash and download a new copy from the App Store.
To know more about how and why Chrome is causing serious trouble, read up here:
https://www.chromeisbad.com
And, although they are doing nothing, you should take to opportunity to do the "clean up" indicated by Etrecheck.
These are files that point to stuff that has been removed, but still remain there in the LaunchAgents and LaunchDaemons folders. Just rerun Etrecheck and follow the instructions to delete them.