Loseless via AirPlay

Hello ondersar,

Thanks for visiting Apple Support Communities. We understand you're wanting to know if you can use AirPlay capable speakers to listen to lossless audio in Apple Music. As it turns out, Bluetooth connections are not supported unless you're using AirPods, AirPods Pro, AirPods Max, or Beats wireless headphones. Those details and more can be found in the following guide: About lossless audio in Apple Music

Thanks again, and take care.

Currently it would seem the answer is no.

Airplay 2 specs ought to allow it, but this feature may need to be enabled by Apple and on endpoints even if endpoints are capable of 24 bit playback.